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A.235

IN-HOUSE IMAGEJ PLUG-IN FOR THE QUALITY ASSURANCE OF DYNAMIC

MULTI LEAF COLLIMATOR

C. Zucchetti

*

, M. Iacco, C. Fulcheri, R. Tarducci.

Medical Physics Department,

Santa Maria della Misericordia Hospital, Perugia, Italy

Introduction:

The purpose of this work is to introduce an automated pro-

cedure for quality control for the linac multi leaf collimator (MLC), working

in dynamic mode, using Gafchromic film. An in-house image-processing

tool was developed, capable of performing an automatic analysis of the film

pattern produced by an irradiation test available on the VARIAN system.

Materials and methods:

Quality-control procedures were performed ac-

cording to AAPM report 82. EBT2 films were irradiated with a VARIAN DHX

linac, equipped with a Millennium 120 MLC, and subsequently scanned.

A garden fence and gap moving pattern were used to monitor positions

and leaf speeds, respectively. An automated image processing tool was de-

veloped using ImageJ, a Java-based free software for image analyses. Our

plug-in allows for (1) film orientation, (2) analysis of the pattern created

by the movement of each leaf pair, fitting the profiles along the longitu-

dinal leaf direction with a Lorentzian function and returning the garden

fence line position and (3) analysis of profile homogeneity of gap moving

pattern to check leaf speed constancy. This plug-in has been tested ana-

lyzing the effects introduced by known errors on leaf position or leaf speeds.

Results:

The automatic image processing tool proved to be useful for evalu-

ating leaf position and speed accuracy. The use of this automated procedure

allows for significant reductions in the time required for quality checks and

improves the detection of delivery errors.

Conclusions:

Fully automated image processing leads to excellent repro-

ducibility of the quality controls and significantly reduces the incidence

of human errors. The plug-in has been developed for the analyses of the

dMLC patterns available on the VARIAN system, but it can be easily adapted

to other systems.

http://dx.doi.org/10.1016/j.ejmp.2016.01.239

A.236

VMAT PLANNING APPROACH TO AVOID SUPERFICIAL UNDERDOSAGE FOR

ACCELERATED PARTIAL BREAST IRRADIATION

F. Zucconi

*

, P. Mancosu, F. Lobefalo, G. Reggiori, A. Stravato, V. Palumbo,

A. Gaudino, L. Paganini, G. Maggi, F. De Rose, S. Tomatis,

M. Scorsetti.

Department of Radiotherapy and Radiosurgery, Istituto Clinico

Humanitas Cancer Center, Rozzano, Italy

Purpose:

Accelerated partial breast irradiation (APBI) is a RT approach that

treats only the lumpectomy bed rather than the whole breast. To account

for breathing and residual motion, a 10 mm virtual expansion of the breast

is usually applied to the CT series (CT_E) and the optimization is per-

formed on an expanded target. However, the recalculation on the original

CT series (CT_O) could be underdosed close to the surface. In this study, a

strategy to increase the target superficial dose is presented.

Material and methods:

Ten APBI cases were randomly selected from the

internal database (41 patients since 06/14). PTV_O was defined on CT_O,

cropping it of 5 mm to the body. Dose prescription was 30 Gy in 5 frac-

tions. PTV_E was defined on CT_E, expanding PTV_O of 10 mm toward the

surface. PTV_E was divided in: PTV_EI (PTV_E cropped of 7 mm from the

CT_O body), PTV_ES (PTV_E between 5 and 7 mm from CT_O body), PTV_EE

(the remaining from PTV_E). Two plans were optimized on the CT_E: (i)

prescribing the same dose to the three PTVs and (ii) PTV_EI

=

30 Gy,

PTV_ES

=

32 Gy, PTV_EE

=

33 Gy. Final dose calculations were performed on

the CT_O. Plan objectives were: D98% (dose received by 98% of the target)

>

95% and D2%

<

107% for PTV, minimizing the Homogeneity Index

(HI

=

D2%

D98%); Plans normalized to PTV_O mean dose were com-

pared in terms of plan objectives findings.

Results:

Opposite behaviors were obtained on the two CT series. On the

CT_E, D98%, D2%, and HI were favorable to (i) (respectively, 94.9% vs 94.5%,

103.7% vs 105.9%, 8.8% vs 11.5%). On the CT_O, D98%, D2%, and HI were fa-

vorable to (ii) (92.3% vs 94.2%, 104.3% vs 104.2%, 12.1% vs 10.1%). In particular,

the superficial volume (i.e. PTV_ES) was the region of highest underdosage

(D98%

=

85.4

±

3.3% for the first approach). Regarding the OAR, minimal

changes were found between the two approaches.

Conclusion:

We demonstrated that a virtual overdosage on the superfi-

cial part of the target is required to fully cover the target.

http://dx.doi.org/10.1016/j.ejmp.2016.01.240

e70

Abstracts/Physica Medica 32 (2016) e1–e70