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Conclusions:

The reported results demonstrate that DIAPIX is a suitable

detector for dosimetric applications. Future plans foresee a new detector

covering a larger area of 2.5

×

7.5 cm

2

and a new prototype to be em-

ployed as a transmission detector, mounted on the LINAC gantry.

This work has been supported by the experiments INFN CSN5 DIAPIX and

IRPT/MIUR.

http://dx.doi.org/10.1016/j.ejmp.2016.01.225

A.222

MULTICENTRE STUDY OF RELATIVE DOSIMETRY MEASUREMENTS USING

RAZOR NEW SILICON DIODE

C. Talamonti

*

, a ,

M.D. Falco

b ,

L. Barone

c ,

E. Di Castro

d

, C. Iervolino

e ,

S. Luxard

o f ,

G. Pastor

e g ,

M.C. Pressell

o h ,

A. Vaian

o i ,

P. Mancosu

j .

a

Università

degli studi di Firenze, Azienda Ospedaliera Universitaria Careggi, Firenze, Italy;

b

Ospedale SS. Annunziata, Università di Chieti, Chieti, Italy;

c

A.R.N.A.S. Garibaldi,

Catania, Italy;

d

Policlinico Umberto I, Roma, Italy;

e

A.O.S. G. Moscati, Avellino,

Italy;

f

Ospedale Asl 1 Massa e Carrara, Carrara, Italy;

g

A.S.L., Lecce, Italy;

h

AO

San Camillo Forlanini, Roma, Italy;

i

A.S.L 3, Pistoia, Italy;

j

Humanitas Milano,

Milano, Italy

Introduction:

In this study an Italian multicentre evaluation of small field

output factors (OFs) and field penumbras of different linear accelerator

manufacturers using a silicon diode of new generation is presented. The

main goal is to provide indications, for each linac model, on small field do-

simetry measurements that could be used by those centers which intend

to implement new and performing treatment techniques.

Materials and methods:

Among 34 radiotherapy centres which took part

in the project, different LINACs were available: 2 Siemens, 13 Elekta Synergy

Agility and BM, 12 Varian CLINAC and 7 Varian True Beam. The same pro-

tocol was used by each centre. A flat ionization chamber was fixed on the

gantry as reference and the IBA unshielded silicon diode RAZOR was used.

The diode was positioned at the isocentre (d

=

10 cm SSD 90 cm) in water

phantom. In-cross line beam profiles were used to calculate the effective

field size (FS_E), defined as (A*B)^0.5.OFs as a function of FS_E, and nominal

field size (FS), ranging from 0.6 to 5 cm, was calculated and normalized to

the 3 cm FS.

Results:

Penumbra measurements were in agreement with each other for

each FS and accelerator model. The mean values of OFs of all LINACs were

found to be in good agreement within a few per mille up to 1 cm FS. In

the smallest fields, the agreement was within few per cent and for

FS

=

0.6 cm was about 10%. For FS below 1 cm, a different trend is evident

depending on different accelerator manufacturer and different models from

the same vendor. Considering the FS_E, the agreement increased especial-

ly for Varian where a st.dev of 8% was found for FS

=

0.6 cm. This was mainly

due to FS which differed from FS_E up to 15%.

Conclusions:

The good agreement among data from different accelera-

tors indicate that RAZOR can be used with good accuracy to perform

measurements in small fields, and that our reported data can be used by

other centres as indicative values, especially when suitable detectors are

not available.

http://dx.doi.org/10.1016/j.ejmp.2016.01.226

A.223

BEAM DELIVERY CHECK AND IN-VIVO DOSIMETRY DURING BREAST

RADIOTHERAPY TREATMENT

C. Talamonti

* , a ,

L. Marrazzo

b ,

C. Arilli

b ,

C. Galeott

i b ,

M. Casati

b ,

S. Calusi

a ,

C. Domizi

a ,

A. Fidanzio

c ,

I. Meattini

b ,

S. Scoccianti

b ,

P. Bonomo

b ,

A. Piermattei

c ,

S. Pallotta

a .

a

Università degli Studi di Firenze, Azienda

Ospedaliera Universitaria Careggi, Firenze, Italy;

b

Azienda Ospedaliera

Universitaria Careggi, Firenze, Italy;

c

Università Cattolica del Sacro Cuore, Roma,

Italy

Introduction:

The goal of this study is to verify the delivery of the pre-

scribed dose during radiotherapy treatment using the integral quality

monitoring (IQM) device (iRT Systems GmbH, Koblenz, Germany) and the

portal imaging together with the software SoftDiso (Best Medical Italy Srl)

for in-vivo measurements. Furthermore the ability in detecting positional

and delivery errors intentionally introduced in breast treatments was studied.

Materials and methods:

IQM consists of a large area ionization chamber,

with a gradient in the electrode plate separation, to be mounted on the

accelerator gantry. It is an independent on-line beam monitoring system

able to verify the accuracy and consistency of beam delivery during each

treatment session. The software SoftDiso permits to evaluate the dose at

the isocenter on the basis of portal images acquired during the delivery

and it allows to compare dose distributions at the isocenter plane of dif-

ferent acquisitions.

3DCRT and IMRT plans were calculated on a phantom and small delivery

errors were induced to simulate deviation on the treatment plans due to

delivery problems and/or to a wrong positioning of the phantom. The

phantom used was the Anderson Rando modified to mimic a female torso

by adding two silicone gel breast implants.

Results:

IQM can detect, with a precision of per mille, errors due to small

changes in MU and field dimensions, while SoftDiso detects discrepancy

on dose reconstructed with a precision of 5%. The combined use of the two

systems allows to identify the source of error (phantom misalignment or

changes in the beam).

Conclusions:

The concurrent use of the two tested systems allow for a check

of the correct functioning of all components in the radiotherapy chain, in-

cluding the treatment planning, the delivery system and the patient

positioning and thus play an important role in meeting the needs of modern

and upcoming radiotherapy QA.

http://dx.doi.org/10.1016/j.ejmp.2016.01.227

A.224

QUALITY ASSURANCE TOOLS FOR RISK MANAGEMENT

S. Tomatis

*

, V. Palumbo, G. Maggi, A. Gaudino, G. Reggiori, F. Lobefalo,

A. Stravato, F. Zucconi, L. Paganini, G.R. D’Agostino, P. Navarria, P. Mancosu,

M. Scorsetti.

Humanitas Research Hospital, Rozzano, Italy

Purpose:

To develop proper quality indices to increase the control of the

workflow in radiotherapy by a quantitative analysis of data extracted from

the R&V system database of our radiotherapy department.

Materials and methods:

Several parameters related to delivery modality,

use of flattened (FF) or unflattened (FFF) beams, pretreatment imaging and

other planning details were extracted for each patient by proper SQL que-

rying of the database. These features were analyzed to derive indicators

for radiotherapy treatment quality and workflow monitoring. Impact of

hypofractionation was quantified by considering the incidence of fraction

doses up to 3 Gy against higher doses. The application of IGRT was mea-

sured to quantify the quality of patient positioning. For a specific

hypofractionated protocol of breast treatment (48 Gy/15 fr), an indicator

was developed to verify that the total number of effective fractions does

not exceed the number of the planned ones.

Results:

Data show an increasing trend in the number of new patients per

year (2500 in 2014). The fraction of VMAT treatments increased from 26.2%

in 2010 to about 85% in 2014. Since 2010, median treatment beam on time

(BOT) for fraction doses above 12 Gy decreased down to less than 2 minutes

in 2014 as for every treatment. In the last 5 years, use of hypofractionation

has grown from 19.2% to about 48.3% of treatments. In 2014 IGRT was

applied to more than 80% of all treatments and always performed in the

first fraction for all patients. Evaluation of excess time involved in the

hypofractionated breast protocol was found to be always below 5 days.

Conclusion:

The introduction of new protocols coupled to a growing com-

plexity of treatments led to higher doses per fraction delivered in acceptable

times for a better patient overall comfort. The evaluation of IGRT frequen-

cy and excess therapy time using our indicators was found to be suitable

to obtain high quality standards in essential parts of the radiotherapy work-

flow in our center.

http://dx.doi.org/10.1016/j.ejmp.2016.01.228

e66

Abstracts/Physica Medica 32 (2016) e1–e70