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Correct Response

Dose reduction

90%

4%

85%

15%

80%

22%

Conclusions:

For very high and very low dose levels, the Radiology De-

partment performance was similar for both ASIR and FBP algorithms. It has

been found that there is a certain dose level at which ASIR enhances the

“diagnostic capability” with respect to FBP and shows its maximum

performance.

http://dx.doi.org/10.1016/j.ejmp.2016.01.308

B.304

ANALYSIS ON PHANTOM IMAGES BETWEEN 2D SYNTHESIZED

MAMMOGRAPHY (SM) FROM DIGITAL BREAST TOMOSYNTHESIS (DBT)

AND FLAT FIELD MAMMOGRAPHY (FFDM)

R. Rosasco

*

, F. Bisi, N. Canevarollo.

Fisica Sanitaria A.S.L. 3 Genovese, Genova,

Italy

Introduction:

In mammography DBT, combined with 2D mammography

(combo), has better performance than conventional FFDM, improving cancer

detection by reducing the superimposition of breast structures.

In recent years companies have developed software to generate SM views

from a DBT dataset. Clinical retrospective studies, analyzing the perfor-

mance of SM associated to DBT compared to conventional 2D alone,

underline that SM offers a dosimetric benefit to the patients, since the ra-

diation dose comes only from DBT instead of combo exposure, and a contrast

improvement in calcifications. No significant differences in diagnostic ac-

curacy appear between SM and FFDM.

The aim of this study is to compare FFDM and SM, acquiring different phan-

toms, with some objective representative parameters.

Materials and Methods:

In order to compare FFDM with SM generated by

DBT, we acquired phantom images in combo mode, using a Hologic unit

with a dedicated software (C-view) to obtain SM.

We used different types of phantoms: contrast, geometric and details phan-

toms and PMMA slabs of different thicknesses with Al details placed on

the surface and at various depths in the phantom. Initially we defined the

most representative acquisition configurations and which physical param-

eters to study.

Results:

The exposures have beenmade with the phantoms positioned hor-

izontally and skewed on the detector plane in order to have the inside

phantoms details at different depths, to simulate the condition of a real breast.

2D and C-View images have been processed with ImageJ to obtain quan-

titative assessments of contrast and resolution of details, evaluating also

the trend of SNR by increasing the thickness of PMMA slabs.

Conclusion:

This preliminary work shows a better performance of SM than

FFDM in contrast values but a loss in spatial resolution parameters, espe-

cially when details contrasts decrease. The results obtained in phantoms

become significant in the clinical setting; moreover there is an agree-

ment with literature data.

http://dx.doi.org/10.1016/j.ejmp.2016.01.309

B.305

EVALUATION OF OPERATOR AND PATIENT DOSE DURING

INTERVENTIONAL CARDIOLOGY PROCEDURES

V. Salamone

* , a ,

G. Mannino

a ,

C. Stancampian

o b ,

S. Inserilli

a ,

A. La Manna

c ,

S. Imm

e c .

a

A.O.U Policlinico Vittorio Emanuele, Catania, Italy;

b

ASST Nord,

Milano, Italy;

c

Divisione Cardiologia, A.O.U. Policlinico Vittorio Emanuele,

Catania, Italy

Introduction:

Purpose of this study is the evaluation of patient and op-

erators dose, in order to optimize the clinical protocols of X-ray

investigations. The study was carried out in reference to some interventional

cardiology procedures and in particular: Transcatheter Aortic Valve System

(TAVI) and Chronic Total Occlusion (CTO). The procedures selected are those

which present greater run times and consequently greater radiation ex-

posure for both the patient and the operators.

Material and Methods:

For the evaluation of the maximum skin dose (MSD)

to the patient radiochromic film (GafChromic XR-RV3) placed to the skin,

has been used, by the entry point of the X-ray beam. The operators dose

have been estimated by using thermoluminescent dosimeters (TLD type

GR200A to LiF (Mg, Cu, P)). A set of three dosimeters have been used for

each operator, one for the whole body, one for the extremity and one for

the eye lens. To optimize the operating protocols was necessary to record

the parameters of exposure, and the position occupied by operators, rel-

ative to the X-ray source. The recorded exposure parameters were: voltage,

current, fluoroscopy time and number of images, and was also written down

the dose-area product (DAP), whose main application is the ability to create

a database of values reference, to be used as a guide for the purposes of

procedures optimization.

Conclusion and Results:

The measurements have allowed the construc-

tion of a correlation between the evaluation of the MSD to the patient, and

the DAP, recorded from the radiological equipment, which allows us to es-

timate the maximum skin dose for each patient. The dose to the two

monitored operators, has been correlated with the patient dose. This allowed

us to estimate, from the values obtained for the patient, the dose to the

operator for each specific procedure, optimizing the operating modes.

http://dx.doi.org/10.1016/j.ejmp.2016.01.310

B.306

IMAGE QUALITY IN SYNCHROTRON RADIATION BREAST CT

A. Sarno

* , a ,

G. Mettivie

r a ,

F. Di Lillo

a ,

B. Golosio

b ,

P. Oliva

b ,

R. Longo

c ,

P. Russo

a .

a

Dipartimento di Fisica, Università di Napoli Federico II and INFN

Sez. Napoli, Napoli, Italy;

b

Universita’ di Sassari and INFN Sez. di Cagliari,

CagliarI, Italy;

c

Dipartimento di Fisica and INFN Sezione di Trieste, Universita’

di Trieste, Trieste, Italy

Introduction:

The goal of the SYRMA-CT project is the first in vivo, free-

space propagation-based phase-contrast 3D imaging of the pendant

uncompressed breast with monochromatic X-ray synchrotron radiation (SR)

at the ELETTRA facility (Trieste, Italy), for breast cancer diagnosis. The

imaging performance of the CT scanner and the dosimetry protocol was

investigated.

Materials and Methods:

The uncompressed breast is scanned with laminar

X-ray beam at 38 keV. The breast-to-detector distance is 2 m and pixel pitch

of the single-photon counting CdTe detector is 60 μm. The modulation trans-

fer function (MTF) of the scanner was evaluated together with the contrast

to noise ratio (CNR) and microcalcification visibility in a mammographic

phantom (CIRS phantom BR50/50 mod. 014AD) at a low radiation dose

(about 4.5 mGy glandular dose in the irradiated section), eligible for in vivo

breast imaging. The influence of phase retrieval (transport-of-intensity al-

gorithm) on the 3D images was evaluated. The CT slices were reconstructed

via filtered-back projection algorithm.

Results:

The system spatial resolution (at 10% MTF) was 6.7 1/mm for at-

tenuation imaging and 2.5 1/mm in the phase-retrieved images. The CNR

increased by one order of magnitude after phase retrieval; microcalcifications

with diameter down to 0.130 mm were visible in both cases. A global index

indicated the superior performance of phase imaging compared to atten-

uation imaging.

Conclusions:

The SR CT scans of the test object and breast phantom showed

the technical feasibility of SR breast CT in terms of spatial resolution and

contrast for in vivo 3D imaging with a dose comparable to that of two-

viewmammography. Phase-retrieved images showed the best performance

in the trade-off between spatial resolution and image noise.

Acknowledgments:

Thanks to all members of the SYRMA-CT collabora-

tion for the useful discussions and contribution to the measurements.

http://dx.doi.org/10.1016/j.ejmp.2016.01.311

B.307

PERSONNEL REAL TIME DOSIMETRY IN INTERVENTIONAL RADIOLOGY

L. Servoli

*

, a ,

M. Paolucci

a , b ,

A. Pentiricci

c ,

P. Placidi

d , a ,

D. Magalotti

e , a ,

S. Fabiani

f , a ,

A. Calandra

g ,

L. Bissi

h , a ,

A. Maselli

b

, M. Scarpignato

b ,

R. Di Lorenzo

a , b ,

R. Cicion

i g ,

A. Scorzoni

d , a ,

L. Colleluori

d ,

S. Chiocchini

g ,

N. Forini

g , a ,

A.C. Di Pilato

g ,

F.P. Cappotto

b .

a

Istituto Nazionale di Fisica

Nucleare, Sezione Perugia, Perugia, Italy;

b

ASL 2 Umbria, Foligno (PG), Italy;

c

ASL 1 Umbria, Città di Castello (PG), Italy;

d

University of Perugia, Dip. di

Ingegneria, Perugia, Italy;

e

University of Modena e Reggio Emilia, Dip.

e90

Abstracts/Physica Medica 32 (2016) e71–e96